"
RustGPT: A pure-Rust transformer LLM built from scratch
Removing newlines in FASTA file increases ZSTD compression ratio by 10x
Language Models Pack Billions of Concepts into 12k Dimensions
Folks, we have the best π
Betty Crocker broke recipes by shrinking boxes
PythonBPF – Writing eBPF Programs in Pure Python
Celestia – Real-time 3D visualization of space
Grapevine canes can be converted into plastic-like material that will decompose
Which colours dominate movie posters and why?
A qualitative analysis of pig-butchering scams
NASA's Guardian Tsunami Detection Tech Catches Wave in Real Time
Human writers have always used the em dash
For Good First Issue – A repository of social impact and open source projects
Sandboxing Browser AI Agents
Omarchy on CachyOS
Which NPM package has the largest version number?
Analyzing the memory ordering models of the Apple M1
The $10 Payment That Cost Me $43.95 – The Madness of SaaS Chargebacks
You’re a slow thinker. Now what?
Learning Lens Blur Fields
Titania Programming Language
Death to Type Classes
OCSP Service Has Reached End of Life
Why We Spiral
Writing an operating system kernel from scratch
Page Object (2013)
A set of smooth, fzf-powered shell aliases&functions for systemctl
Nicu's test website made with SVG (2007)
Introduction to GrapheneOS
Trigger Crossbar
AMD Turin PSP binaries analysis from open-source firmware perspective
Show HN: A store that generates products from anything you type in search
Repetitive negative thinking associated with cognitive decline in older adults
Read to forget
Xrust – XPath, XQuery, and XSLT for Rust
The Mac App Flea Market
Models of European metro stations
Decentralized YouTube alternative adds livestream scheduling in new release
The AI-Scraping Free-for-All Is Coming to an End
The PC was never a true 'IBMer'
Cex.C – Comprehensively EXtended C Language
Observable Notebooks Data Loaders
La-Proteina
High Altitude Living – 8,000 ft and above (2021)
Gentoo AI Policy
MIT-MC CP/M archive files, 1979-1984
CorentinJ: Real-Time Voice Cloning (2021)
Show HN: Dagger.js – A buildless, runtime-only JavaScript micro-framework
FakeIt: C++ Mocking Made Easy
Implementing namespaces and coding standards in WordPress plugin development
macOS Tahoe is certified Unix 03 [pdf]
Patela: A basement full of amnesic servers
Bank of Thailand freezes 3M accounts, sets daily transfer limits to curb fraud
ChatControl update: blocking minority held but Denmark is moving forward anyway
Dynamic Bird Migration Map
The unreasonable effectiveness of modern sort algorithms
Gleam is my new obsession
Irrlicht Engine – a cross-platform realtime 3D engine
Geedge and MESA leak: Analyzing the great firewall’s largest document leak
Cannabis use associated with quadrupled risk of developing type 2 diabetes
Gemini (2023)
Not all browsers perform revocation checking
Eye drops could replace glasses or surgery for longsightedness, study says
Two Slice, a font that's only 2px tall
A single, 'naked' black hole confounds theories of the young cosmos
How Container Filesystem Works: Building a Docker-Like Container from Scratch
Accelerated Game of Life with CUDA / Triton
SpikingBrain 7B – More efficient than classic LLMs
Interactive Tree of Life Explorer
Vibe Coding Is Making Braindead Coders
Fukushima insects tested for cognition
Adding OR logic forced us to confront why users preferred raw SQL
The world of Kenya's shadow scholars paid to write essays for UK students
Website is hosted on a disposable vape
Recreating the US/* time zone situation
Deep Dive into SATA, USB and PCI Express on AMD Turin
Pass: Unix Password Manager
FBI Alert: Two Cybercriminal Groups Are Actively Compromising Salesforce
A Trick for Backpropagation of Linear Transformations
Lexy: A parser combinator library for C++17
UTF-8 is a brilliant design
Library of Time
Orange rivers signal toxic shift in Arctic wilderness
The Socratic Journal Method: A Simple Journaling Method That Works
The Software Engineers Paid to Fix Vibe Coded Messes
Weird CPU architectures, the MOV only CPU (2020)
Refurb Weekend: Silicon Graphics Indigo² Impact 10000
How older parents divorce affects their adult children
Will AI be the basis of many future industrial fortunes, or a net loser?
Turn MEP prompts into AutoCAD drawings in minutes
A new theory of China's rise: rule by engineers
Show HN: Vicinae – A native, Raycast-compatible launcher for Linux
Starlink is currently experiencing a service outage
Learn Rust the Right Way
Vibe coding has turned senior devs into 'AI babysitters'
Show HN: Small Transfers – charge from 0.000001 USD per request for your SaaS
I used standard Emacs extension-points to extend org-mode
My thoughts on renting versus buying
Many hard LeetCode problems are easy constraint problems
J-Link RTT for the Masses using Semihosting on ARM
How the restoration of ancient Babylon is drawing tourists back to Iraq
Show HN: PaperSync, making ArXiv papers collaborative
Japan sets record of nearly 100k people aged over 100
Show HN: Ultraplot – A succint wrapper for matplotlib
SkiftOS: A hobby OS built from scratch using C/C++ for ARM, x86, and RISC-V
486Tang – 486 on a credit-card-sized FPGA board
Magical systems thinking
Perceived Age (2024)
AMD’s RDNA4 GPU architecture
Mago: A fast PHP toolchain written in Rust
Tips for installing Windows 98 in QEMU/UTM
L1TTL3 PAWS – Cat glider with procedural art and levels in only 13kb
Life, work, death and the peasant: Rent and extraction
The idea of /usr/sbin has failed in practice
Does All Semiconductor Manufacturing Depend on Spruce Pine Quartz? (2024)
My first impressions of Gleam
Visual programming is stuck on the form
How FOSS Projects Handle Legal Takedown Requests
How to use Claude Code subagents to parallelize development
Cat Aquariums
Four-year wedding crasher mystery solved
How to join or concat ranges, C++26
AI coding
RIP pthread_cancel
Corporations are trying to hide job openings from US citizens
GrapheneOS accessed Android security patches but not allowed to publish sources
QGIS is a free, open-source, cross platform geographical information system
AI False information rate for news nearly doubles in one year
Perrinn 424 – An open access electric hyper car designed for racing
Windows-Use: an AI agent that interacts with Windows at GUI layer
Myocardial infarction may be an infectious disease
An Inline Cache Isn't Just a Cache
Meow: Yet another modal editing on Emacs
I don't like curved displays
The case against social media is stronger than you think
OpenAI Grove
Legal win
Racintosh Plus – Rackmount Mac Plus
‘Overworked, underpaid’ humans train Google’s AI
Qwen3-Next
The treasury is expanding the Patriot Act to attack Bitcoin self custody
How Ruby executes JIT code
Raspberry Pi Synthesizers – How the Pi is transforming synths
Show HN: I made a generative online drum machine with ClojureScript
Reshaped is now open source
Oq: Terminal OpenAPI Spec Viewer
How to get samples back from Mars
Reduce bandwidth costs with dm-cache: fast local SSD caching for network storage
An open-source maintainer's guide to saying “no”
Adam (YC W25) Is Hiring to Build the Future of CAD
FFglitch, FFmpeg fork for glitch art
Can I Give You Some Advice?
Safe C++ proposal is not being continued
California Wants to Ban 'Forever Chemicals' in Pans. These Chefs Say Don't Do It
Using Emacs Org-Mode With Databases: A getting-started guide
Social media promised connection, but it has delivered exhaustion
Energy-Based Transformers [video]
Resizing images in Rust, now with EXIF orientation support
Imagine putting DRM in a battery to void warranties [video]
CVC acquires majority stake in Namecheap for $1.5B
Show HN: CLAVIER-36 – A programming environment for generative music
Java 25's new CPU-Time Profiler
OCI Registry Explorer
Gestational diabetes tied to rises in ADHD and autism
EFF to court: The Supreme Court must rein in secondary copyright liability
Removing yellow stains from fabric with blue light
Lessons in disabling RC4 in Active Directory (2021)
Rails on SQLite: new ways to cause outages
Logfire – OpenTelemetry based tracing SaaS
Open Source SDR Ham Transceiver Prototype
Ollee Watch: Turn your classic Casio watch into a smartwatch
Float Exposed
Why our website looks like an operating system
NT OS Kernel Information Disclosure Vulnerability
Top model scores may be skewed by Git history leaks in SWE-bench
VaultGemma: The most capable differentially private LLM
Cyber-scam camp operators shift ops to vulnerable countries as sanctions strike
AirPods live translation blocked for EU users with EU Apple accounts
Motorola, Intel, IBM Make a Mainframe in a PC – The PC XT/370
An engineering history of the Manhattan Project
3D modeling with paper
How to become a pure mathematician or statistician (2008)
The HackberryPi CM5 handheld computer
Unauthorized Windows/386
The rules behing Rust functions
‘Robber bees’ invade apiarist’s shop in attempted honey heist
The value of bringing a telephoto lens
Toddlerbot: Open-Source Humanoid Robot
A Web Framework for Zig
Show HN: Building a Deep Research Agent Using MCP-Agent
US power use to reach record highs in 2025 and 2026, EIA says
Center for the Alignment of AI Alignment Centers
Pontevedra, Spain declares its entire urban area a \"reduced traffic zone\"
Rust: A quest for performant, reliable software [video]
EU court rules nuclear energy is clean energy
Show HN: Term.everything – Run any GUI app in the terminal
Show HN: GitHub repo with 180 tools for investing
Show HN: I made pgdbtemplate to cut PostgreSQL test time by 1.5x using templates
Discovery of a new satellite or ring arc around Quaoar
Chatbox app is back on the US app store
ButterflyQuant: Ultra-low-bit LLM Quantization
PA-RISC Performance and History
Cave Drops 500ft Through a Mountain Into a Corn Field [video][19 mins]
Vector database that can index 1B vectors in 48M
Design Principles for Precision Mechatronics
Doom-ada: Doom Emacs Ada language module with syntax, LSP and Alire support
If We Want Bigger Wind Turbines, We're Gonna Need Bigger Airplanes
Claude’s memory architecture is the opposite of ChatGPT’s
I unified convolution and attention into a single framework
Where did the Smurfs get their hats (2018)
Americans Crushed by Auto Loans as Defaults and Repossessions Surge
Defeating Nondeterminism in LLM Inference
All clickwheel iPod games have now been preserved for posterity
Proton Mail suspended journalist accounts at request of cybersecurity agency
Charlie Kirk killed at event in Utah
PgEdge Goes Open Source
Hashed sorting is typically faster than hash tables
Making io_uring pervasive in QEMU [pdf]
Debian 13, Postgres, and the US/* time zones
Advanced Scheme Techniques (2004) [pdf]
Astrophysics Source Code Library
“No Tax on Tips” Includes Digital Creators, Too
Samsung taking market share from Apple in U.S. as foldable phones gain momentum
Antlr-Ng Parser Generator
Revanced Team Gets DMCA from Spotify
Doorbell prankster that tormented residents of apartments turns out to be a slug
I replaced Animal Crossing's dialogue with a live LLM by hacking GameCube memory
Locked-up merchandise is driving customers away
Mathematics Discovering Its Consciousness: Lasso Estimator as Cosmic Backdoor
Why do browsers throttle JavaScript timers?
Learning lessons from the loss of the Norwegian frigate Helge Ingstad
Examples from The LaTeX Companion book (3rd edition)
Writing an operating system kernel from scratch – RISC-V/OpenSBI/Zig
RFC9460: SVCB and HTTPS DNS Records
Introduction to Nyquist and Lisp Programming
Launch HN: Recall.ai (YC W20) – API for meeting recordings and transcripts
Ancient DNA solves Plague of Justinian mystery to rewrite pandemic history
Chat Control faces blocking minority in the EU
New bacteria, and two potential antibiotics, discovered in soil
An annual blast of Pacific cold water did not occur
Danish supermarket chain is setting up \"Emergency Stores\"
What happens when you get hit by a car in San Francisco
Classic GTK1 GUI Library
China's auto regulators eye ban on retractable door handles, report says
iPhone Air
Automate compile_flags for C/C++ projects on the Zig build system
Equatorial Guinea enforces yearlong internet outage for island that protested
Why are so many young, fit, non-smoking women getting lung cancer?
“Learning how to Learn” will be next generation's most needed skill
Can you help us crack the Dickens Code?
Semantic Line Breaks (2017)
What goes into making an OS to be Unix compliant certified?
Behind the scenes of Bun Install
Using pollen to make paper, sponges, and more
A desktop environment without graphics (tmux-like)
ChatGPT Developer Mode: Full MCP client access
Mozilla Firefox Is Officially Getting MKV Video Support
Behind Kamathipura's Closed Doors
Ten Years of D3D12
Mistral raises 1.7B€, partners with ASML
Kerberoasting
California lawmakers pass SB 79, housing bill that brings dense housing
Ships are sailing with fake insurance from the Norwegian Ro Marine
Nano Banana image examples
Porsche demonstrates inductive EV charging at IAA
Gregg Kellogg has died
Soviet Maps
Kefir: Solo-developed full C17/C23 compiler with extensive validation
Signal Secure Backups
Tarsnap is cozy
E-paper display reaches the realm of LCD screens
Lula: Brazilian Democracy and Sovereignty Are Non-Negotiable
Gene-edited pancreatic cells transplanted into a patient with type 1 diabetes
A Few Notes on Ratelimiting
Show HN: TailGuard – Bridge your WireGuard router into Tailscale via a container
California age verification bill backed by Google, Meta, OpenAI heads to Newsom
How the tz database works (2020)
Humanely dealing with humungus crawlers
K2-think: A parameter-efficient reasoning system
From burner phones to decks of cards: NYC teens adjusting to the smartphone ban
\"Bottlebrush\" particles deliver chemotherapy payloads directly to cancer cells
DeepCodeBench: Real-World Codebase Understanding by Q&A Benchmarking
A tech-law measurement and analysis of event listeners for wiretapping
Claude now has access to a server-side container environment
New Bill Would Give Marco Rubio \"Thought Police\" Power to Revoke U.S. Passports
Disposable Code Is Here to Stay, but Durable Code Is What Runs the World
UC Berkeley Gives Names of Students and Faculty to Government for Antisem Probe
GrapheneOS and forensic extraction of data (2024)
Show HN: Making a cross-platform game in Go using WebRTC Datachannels
US High school students' scores fall in reading and math
Show HN: C++ Compiler Support Page
I didn't bring my son to a museum to look at screens
Show HN: Aris – a free AI-powered answer engine for kids
Intel's E2200 \"Mount Morgan\" IPU at Hot Chips 2025
Gambit: An efficient implementation of the Scheme programming language
R-Zero: Self-Evolving Reasoning LLM from Zero Data
Building my childhood dream PC
The challenge of maintaining curl
The Helix Text Editor (2024)
Jeopardy’s most controversial moment was years in the making
Trump: Lot of People on the Left \"Are Already Under Investigation\"
Things you can do with a debugger but not with print debugging
Launch HN: Ghostship (YC S25) – AI agents that find bugs in your web app
The rise of async AI programming
Show HN: An MCP Gateway to block the lethal trifecta
Phone batteries are getting more compact, but the US is missing out
A beginner's guide to extending Emacs
Toxic Fumes Are Leaking into Airplanes, Sickening Crews and Passengers
Show HN: Bottlefire – Build single-executable microVMs from Docker images
Bulletproof host Stark Industries evades EU sanctions
DOOMscrolling: The Game
Lumina-DiMOO: An open-source discrete multimodal diffusion model
Wimpy vs. McDonald's: The Battle of the Burgers
Conway's Game of Life, but musical
Microsoft is officially sending employees back to the office
OrioleDB Patent: now freely available to the Postgres community
Emotional Manipulation by AI Companions
Navy doctor fired after right-wing activists find pronouns on social media
Public Suffix List
Polylaminin, a drug considered capable of reversing spinal cord injury
Mapping to the PICO-8 palette, perceptually
The MacBook has a sensor that knows the exact angle of the screen hinge
Anscombe's Quartet
OpenAI’s latest research paper demonstrates that falsehoods are inevitable
Real-time AI hallucination detection with timeplus: A chess example
EPA Seeks to Eliminate Critical PFAS Drinking Water Protections
Where did DNSSEC go wrong?
OpenAI Realizes It Made a Terrible Mistake
How I solved PyTorch's cross-platform nightmare
First 'perovskite camera' can see inside the human body
Show HN: YC Startup Map – A Map Visualization of the YC Startup Directory
XFN – XHTML Friends Network (2003)
KDE launches its own distribution
Inboxfuscation: Because Rules Are Meant to Be Broken
Jiratui – A Textual UI for interacting with Atlassian Jira from your shell
Strong Eventual Consistency – The Big Idea Behind CRDTs
The 100MHz 6502
YouTube is a mysterious monopoly
Full Moon: Seestar S50 vs. Samsung S25
Clojure's Solutions to the Expression Problem
C++20 Modules: Practical Insights, Status and TODOs
Beyond package management: How Nix refactored my digital life
How Britain built some of the world’s safest roads
Show HN: Haystack – Review pull requests like you wrote them yourself
Backprompting: Leveraging synthetic production data for health advice guardrails
I have left Branch and am no longer involved with Nova Launcher
A love letter to the CSV format (2024)
How Palantir is mapping the nation’s data
UK launches Project Octopus to deliver interceptor drones to Ukraine
Anthropic agrees to pay $1.5B to settle lawsuit with book authors
Spiral
Some thoughts on personal Git hosting
Adjacency Matrix and std:mdspan, C++23
iPhone dumbphone
Grade 2 Braille
Why is Japan still investing in custom floating point accelerators?
The Cudy AX3000 Wi-Fi 6 System (With OpenWRT)
Power series, power serious (1999) [pdf]
Hypervisor in 1k Lines
George Bernard Shaw by G. K. Chesterton (1909)
Subgrid: How to line up elements to your heart's content
Immunotherapy drug clinical trial results: half of tumors shrink or disappear
My Quarterly System Health Check-In: Beyond the Dashboard
DuckDB NPM packages 1.3.3 and 1.29.2 compromised with malware
Turgot Map of Paris
My Favorite PostgreSQL 18 Feature: Virtual Generated Columns
Becoming the person who does the thing
Go for Bash Programmers – Part II: CLI Tools
Why Is Taiwan the Poorest Among Developed Countries?
Wysiwid: What you see is what it does
Rewriting Dataframes for MicroHaskell
People Who Hunt Down Old TVs
Digital Museum of Planetary Mapping
ICE is using fake cell towers to spy on people's phones
Fraudulent Publishing in the Mathematical Sciences
ApeRAG: Production-ready GraphRAG with multi-modal indexing and K8s deployment
NASA finds Titan's lakes may be creating vesicles with primitive cell walls
A South Dakota county drove away millions in solar energy
Using Claude Code to modernize a 25-year-old kernel driver
Amazon EC2 M4 and M4 Pro Mac Instances
Hot Chips 2025: Session 1 – CPUs
AI might yet follow the path of previous technological revolutions
Graphene just broke a fundamental law of physics
Immich – High performance self-hosted photo and video management
WhoBIRD is now deprecated on certified Android devices
We all dodged a bullet
Show HN: DWS OS, a Plan 9 Inspired Web “OS”
Velox: A composable and extensible C++ execution engine library
KeepassDX has landed passkeys support (beta)
ERP Therapy Sucks
We already live in social credit, we just don't call it that
Close the loop: analytics that teach your chatbot to fix itself
Show HN: wcwidth-o1 – Find Unicode text cell width in no time for JavaScript/TS
Germany is not supporting ChatControl – blocking minority secured
Steam Censorship of Adult Games Shows How Payment Processors Wield Immense Power
27 GPU hours, BAGEL with self-supervised post-training beats FLUX-Kontext
Harvey Mudd Miniature Machine
Longhorn – A Kubernetes-Native Filesystem
Vietnam to close 86M bank accounts for lack of biometric data
AI-generated medical data can sidestep usual ethics review, universities say
Kenvue stock drops on report RFK Jr will link autism to Tylenol during pregnancy
Contracts for C
Ankit Gupta Joins YC as General Partner
Leonardo da Vinci’s Y chromosome shared by living family descendants
Normal-order syntax-rules and proving the fix-point of call/cc
Liquid Glass in the Browser: Refraction with CSS and SVG
A critique of package managers
Zoox robotaxi launches in Las Vegas
Seedship – Text-Based Game
The origin story of merge queues
FFmpeg – The Ultimate Guide
Distributing your own scripts via Homebrew
Court rejects Verizon claim that selling location data without consent is legal
Praxos: Personal AI Assistant That Integrates with WhatsApp and Telegram
Is This the End of the Dictionary?
Vinegar: The Tiny Metabolic Hack That Transforms How Your Body Stores Food
The “impossibly small” Microdot web framework
Instruction-Following Pruning for Large Language Models
What I think about when I think about Claude Code
How can England possibly be running out of water?
Protobuffers Are Wrong (2018)
Logging in Go with Slog: A Practitioner's Guide
Rendering flame fractals with a compute shader (2023)
If my kids excel, will they move away?
Bending Spoons acquires Vimeo for $1.38B
Show HN: MemoryMe: An effort to beat Cognitive Decline
The effects of algorithms on the public discourse
We can’t circumvent the work needed to train our minds
Being good isn't enough
Anthropic judge rejects $1.5B AI copyright settlement
A clickable visual guide to the Rust type system
Reverse-engineering Roadsearch Plus, or, roadgeeking with an 8-bit CPU
Experimenting with Local LLMs on macOS
An embarrassing failure of the US patent system: Nintendo's latest patents
Hallucination Risk Calculator
A polyglot's guide to multiple-dispatch (2016)
UTF-8 as told by Rob Pike
Introducing HybridPetya: Petya/NotPetya copycat with UEFI Secure Boot bypass
Learning the soroban as an adult (2022)
Knowledge and memory
Crates.io phishing attempt
Claude's new Code Interpreter review
Picat: A Logic-based Multi-paradigm Language (2014) [pdf]
NPM debug and chalk packages compromised
Children and young people's reading in 2025
China's Great Firewall has its biggest leak ever – source code and docs spill
Tumult and Sympathy – The Letters of Oliver Sacks
I solved a distributed queue problem after 15 years
Harness GitOps on Linux for Seamless Git-First Infrastructure Management
Building a DOOM-like multiplayer shooter in pure SQL
Specialization Saved Medicine. Now It's Holding Us Back
Cuba entirely without power following electric grid collapse
Deluxe Paint on the Commodore Amiga
Your Brain on ChatGPT
Show HN: I made a script that gives me fake calls to escape boring moments
You too can run malware from NPM (I mean without consequences)
Yet Another TypeSafe and Generic Programming Candidate for C
A new experimental Go API for JSON
ARM is great, ARM is terrible, and so is RISC-V
Is This Thing On?
Memory Integrity Enforcement
French platform combines carpooling with cross-border price arbitrage in the EU
Checking if a JavaScript native function is monkey patched (2022)
How many dimensions is this?
Device enabling dogs to form sentences
The Rise and Demise of RSS (2018)
Show HN: Pbar.io – Distributed progress bars that work in terminals and browsers
Jef Raskin's cul-de-sac and the quest for the humane computer
30 minutes with a stranger
Building an ARM64 home server the hard way
Tomorrow's emoji today: Unicode 17.0
Cassette Logic: technology that never dies but is already dead
Dropbox Paper mobile App Discontinuation
Source code for the X recommendation algorithm
GPT-5 Thinking in ChatGPT (a.k.a. Research Goblin) is good at search
Show HN: Consentless – A minimalist, privacy-preserving traffic counter
TikTok has turned culture into a feedback loop of impulse and machine learning
I am giving up on Intel and have bought an AMD Ryzen 9950X3D
Strong Eventual Consistency – The Big Idea Behind CRDTs
China's economy slowdown deepens in August: retail sales, industrial output miss
The maths you need to start understanding LLMs
Apple Debuts iPhone 17
Get Out of Technology
Guy running a Google rival from his laundry room
How many SPARCs is too many SPARCs?
An attacker’s blunder gave us a look into their operations
Password1: Scammers exploit variations of your logins
How RSS beat Microsoft
A Technical Update on Submarine Cables [pdf]
Eternal Struggle
Microsoft doubles down on small modular reactors and fusion energy
Brussels faces privacy crossroads over encryption backdoors
Formally verifying a floating-point division routine with Gappa – part 1
Clankers Die on Christmas
Pgschema – Declarative schema migration for Postgres
De-Clouding: Music
Show HN: Lightweight tool for managing Linux virtual machines
Show HN: CrabCamera – Cross-platform camera plugin for Tauri desktop apps
Calif. construction worker unofficially broke a fabled world record
Show HN: Swimming in Tech Debt
Researchers have found the longest known case of COVID-19 in a person living with HIV. Lasting 776 days, multiple viral populations were present displaying hallmarks of Omicron months before its global emergence. These often heavily mutated genomes are thought to be the source of variants of concern
For stronger bones at any age, replace sitting with light activity. A sweeping review shows that across all ages, even light daily activity protects bone health, while too much sedentary time quietly raises the risk of fractures.
Genetic study suggests ways to catch blood cancer earlier: « New understanding of how mutations interact could pave way for early detection, prevention strategies. »
A US study finds that even modest reductions in access to PrEP could lead to 8,600+ extra HIV infections in 10 years, adding $3.6B in lifetime medical costs.
New technique uses focused sound waves & holograms to control brain circuits in living animals
New Nuclear Rocket Concept Could Slash Mars Travel Time in Half
Cannabis compounds THC and cannabidiol (CBD) have opposing effects on brain function—and combining the two produces more muted changes than THC alone, finds new neuroimaging study in rats to compare how these cannabis-derived compounds alter patterns of communication and blood flow in the brain.
Myeloid progenitor dysregulation fuels immunosuppressive macrophages in tumours
Bioactive molecules unearthed by terabase-scale long-read sequencing of a soil metagenome
Universality in quantum critical flow of charge and heat in ultraclean graphene
Investigating the Metabolic Benefits of Magnetic Mitohormesis in Patients with Type 2 Diabetes Mellitus
Ancient DNA reveals a two-clanned matrilineal community in Neolithic China
Why Event-Driven Systems are Hard?
Falsehoods programmers believe about null pointers
Building a Simple Stack-Based Virtual Machine in Go
A Dumb Introduction to z3. Exploring the world of constraint solvers with very simple examples.
Built a High-Performance Key-Value Datastore in Pure Java
PostgreSQL partitioning, logical replication and other Q&A about PostgreSQL Superpowers
From all truths to (ir)relevancies
Design challenges in building a real-time collaborative photo grid + chat system
Lessons from real aviation accidents for better software engineering (5 you can use this week)
A Comprehensive Guide on Builder Design Pattern with all Flavors & Examples
BEEP-8: Running C/C++20 on an emulated ARM v4a CPU inside the browser
Need Help with Zoom Meeting SDK setup + Where to find SDK Key?
Career advice
built fasterpc bc i was frustrated with the usual distributed service comms, no more rest apis, or heavy MQs
PostgreSQL Field Guide - The reference guide for new users
Nytril: A programming language and a markup language in one
Observer Pattern in Java
Help me start programming
How to Start With Freelance Work as an Engineer
Java is 30 Years Old // Here’s Why It’s Still Winning
So You Want to Host Your Own LLM? Don’t.
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