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Sudden drop in fentanyl overdose deaths linked to Biden-era global supply shock. Study indicates that regulatory actions taken by the Chinese government, following high-level diplomatic engagement with the Biden administration, may be the primary driver behind this unexpected decline in mortality.

People who stop taking weight-loss injections like Ozempic regain weight in under 2 years, study reveals. Analysis finds those who stopped using medication saw weight return 4 times faster compared with other weight loss plans.

Using the same math employed by string theorists, network scientists discover that surface optimization governs the brain’s architecture — not length minimization.

ADHD risk may not be fixed at birth, but shaped by early environments: For children with parents who have elevated ADHD symptoms, a rich and supportive home environment predicted better cognitive functioning and linked to fewer ADHD symptoms in later childhood and adolescence.

Exercise can have a moderate benefit in reducing depressive symptoms, comparable to therapy and antidepressants, according to a meta analysis of randomized controlled trials including nearly 5,000 adults with depression

A new study finds a dog's carbon footprint can exceed their owner's, largely due to the high meat content in wet food. Wet diets generate seven times more emissions than dry kibble. Since meat is carbon-intensive, researchers suggest switching to dry food significantly aids climate efforts.

Researchers found a method to reprogram macrophages inside solid tumors—the deadliest and most resistant cancers—using mRNA. By delivering genetic instructions directly to the tumor, the therapy cleared cancer in mouse models, potentially unlocking a pathway for patients with few options.

Autism-related traits are associated with faster autonomic processing, as measured through pupillary light reflex (PLR) dynamics in infancy, and are also linked to epigenome-wide DNA methylation patterns

Autism shows elevated brain glutamine on 7T MRS, consistent with presumably increased glutamine–glutamate cycling, indicating greater glutamate turnover and recycling demand in adults

“Sam apologized to Alex, so he felt better” — many readers will understand “he” as Sam (the earlier referent). The paper reports that in its ambiguity task, conclusive connectives like “so/therefore” were more often associated with choosing that earlier referent.

Researchers uncover new rules for designing protein-like polymers

Groundbreaking mapping: how many ghost particles all the Milky Way’s stars send towards Earth

Arboviruses manipulate rice’s volatile emissions, protecting insect vectors from natural enemies in the field - Science Advances

We might have been slower to abandon Stack Overflow if it wasn't a toxic hellhole

Tailwind just laid off 75% of their engineering team

Newer AI Coding Assistants Are Failing in Insidious Ways

IBM AI ('Bob') Downloads and Executes Malware

Newer AI Coding Assistants Are Failing in Insidious Ways | IEEE Spectrum

Testing fundamentals I wish I understood earlier as a developer

Python Typing Survey 2025: Code Quality and Flexibility As Top Reasons for Typing Adoption

Tech blogging lessons learned

Template Deduction: The Hidden Copies Killing Your Performance (Part 2 of my Deep Dives)

Everything you might have missed in Java in 2025

pg-status — a lightweight microservice for checking PostgreSQL host status

Sakila25: Updated Classic Sakila Database with 2025 Movies from TMDB – Now Supports Multiple DBs Including MongoDB

AI Is Still Easy to Trick • Katharine Jarmul

What a 1955 Computer Taught Me

Belief Propagation : Obscure Alternative to Backpropagation for Training Reasoning Models

How Developers Use Cursor AI: 6 Easy Tasks Beyond Code Generation

How I Wrote 240,000+ Lines of Production Code in 60 Days Using Claude AI and Eiffel
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